Organic Chemistry David Klein Pdf Download

Posted on  by 

Does anyone in any case have the pdf version of the 2nd edition Solution Manual (for free haha). I found a solution manual which.

Emerald
General
CategoryBeryl variety
Formula
(repeating unit)
Be3Al2(SiO3)6
Crystal systemHexagonal (6/m 2/m 2/m) Space group: P6/mсc
Space group(6/m 2/m 2/m) – dihexagonal dipyramidal
Unit cella = 9.21 Å, c = 9.19 Å; Z = 2
Identification
Formula mass537.50
ColorGreen shades to colorless
Crystal habitMassive to well Crystalline
CleavageImperfect on the [0001]
FractureConchoidal
Mohs scalehardness7.5–8
LusterVitreous
StreakWhite
DiaphaneityTransparent to opaque
Specific gravityAverage 2.76
Optical propertiesUniaxial (−)
Refractive indexnω = 1.564–1.595,
nε = 1.568–1.602
Birefringenceδ = 0.0040–0.0070
None (some fracture-filling materials used to improve emerald's clarity do fluoresce, but the stone itself does not)
References[1]

Emerald is a gemstone and a variety of the mineralberyl (Be3Al2(SiO3)6) colored green by trace amounts of chromium and sometimes vanadium.[2] Beryl has a hardness of 7.5–8 on the Mohs scale.[2] Most emeralds are highly included,[3] so their toughness (resistance to breakage) is classified as generally poor. Emerald is a cyclosilicate.

  • 2Properties determining value
  • 3Emerald mines

Etymology

The word 'emerald' is derived (via Old French: esmeraude and Middle English: emeraude), from Vulgar Latin: esmaralda/esmaraldus, a variant of Latinsmaragdus, which originated in Ancient Greek: σμάραγδος (smaragdos; 'green gem').[4]

Properties determining value

Cut emeralds

Emeralds, like all colored gemstones, are graded using four basic parameters–the four Cs of connoisseurship: color, clarity,cut and carat weight. Normally, in the grading of colored gemstones, color is by far the most important criterion. However, in the grading of emeralds, clarity is considered a close second. A fine emerald must possess not only a pure verdant green hue as described below, but also a high degree of transparency to be considered a top gem.[5]

In the 1960s, the American jewelry industry changed the definition of emerald to include the green vanadium-bearing beryl. As a result, vanadium emeralds purchased as emeralds in the United States are not recognized as such in the UK and Europe. In America, the distinction between traditional emeralds and the new vanadium kind is often reflected in the use of terms such as 'Colombian emerald'.[6]

Color

In gemology,[7] color is divided into three components: hue, saturation, and tone. Emeralds occur in hues ranging from yellow-green to blue-green, with the primary hue necessarily being green. Yellow and blue are the normal secondary hues found in emeralds. Only gems that are medium to dark in tone are considered emeralds; light-toned gems are known instead by the species name green beryl. The finest emeralds are approximately 75% tone on a scale where 0% tone is colorless and 100% is opaque black. In addition, a fine emerald will be saturated and have a hue that is bright (vivid). Gray is the normal saturation modifier or mask found in emeralds; a grayish-green hue is a dull-green hue.[5]

Clarity

Brazilian emerald (grass-green variety of the mineral beryl) in a quartz-pegmatite matrix with typical hexagonal, prismatic crystals.[8]

Emeralds tend to have numerous inclusions and surface breaking fissures. Unlike diamonds, where the loupe standard, i.e. 10× magnification, is used to grade clarity, emeralds are graded by eye. Thus, if an emerald has no visible inclusions to the eye (assuming normal visual acuity) it is considered flawless. Stones that lack surface breaking fissures are extremely rare and therefore almost all emeralds are treated ('oiled', see below) to enhance the apparent clarity. The inclusions and fissures within an emerald are sometime described as jardin (French for garden), because of their mossy appearance.[9] Imperfections are unique for each emerald and can be used to identify a particular stone. Eye-clean stones of a vivid primary green hue (as described above), with no more than 15% of any secondary hue or combination (either blue or yellow) of a medium-dark tone, command the highest prices.[5] The relative non-uniformity motivates the cutting of emeralds in cabochon form, rather than faceted shapes. Faceted emeralds are most commonly given an oval cut, or the signature emerald cut, a rectangular cut with facets around the top edge.

Treatments

Most emeralds are oiled as part of the post-lapidary process, in order to fill in surface-reaching cracks so that clarity and stability are improved. Cedar oil, having a similar refractive index, is often used in this widely adopted practice. Other liquids, including synthetic oils and polymers with refractive indexes close to that of emeralds, such as Opticon, are also used. These treatments are typically applied in a vacuum chamber under mild heat, to open the pores of the stone and allow the fracture-filling agent to be absorbed more effectively.[10] The U.S. Federal Trade Commission requires the disclosure of this treatment when an oil treated emerald is sold.[11] The use of oil is traditional and largely accepted by the gem trade, although oil treated emeralds are worth much less than un-treated emeralds of similar quality. Other treatments, for example the use of green-tinted oil, are not acceptable in the trade.[12] Gems are graded on a four-step scale; none, minor, moderate and highly enhanced. These categories reflect levels of enhancement, not clarity. A gem graded none on the enhancement scale may still exhibit visible inclusions. Laboratories apply these criteria differently. Some gemologists consider the mere presence of oil or polymers to constitute enhancement. Others may ignore traces of oil if the presence of the material does not improve the look of the gemstone.[13]

Emerald mines

A Colombian trapiche emerald

Emeralds in antiquity were mined in Egypt at locations on Mount Smaragdus since 1500 BCE, and India, and Austria since at least the 14th century CE.[14] The Egyptian mines were exploited on an industrial scale by the Roman and Byzantine Empires, and later by Islamic conquerors. Mining ceased with the discovery of the Colombian deposits; only ruins remain.[15]

Colombia is by far the world's largest producer of emeralds, constituting 50–95% of the world production, with the number depending on the year, source and grade.[16][17][18][19] Emerald production in Colombia has increased drastically in the last decade, increasing by 78% from 2000 to 2010.[20] The three main emerald mining areas in Colombia are Muzo, Coscuez, and Chivor.[21] Rare 'trapiche' emeralds are found in Colombia, distinguished by ray-like spokes of dark impurities.

Organic Chemistry David Klein Pdf Download

Zambia is the world's second biggest producer, with its Kafubu River area deposits (Kagem Mines) about 45 km (28 mi) southwest of Kitwe responsible for 20% of the world's production of gem-quality stones in 2004.[22] In the first half of 2011, the Kagem Mines produced 3.74 tons of emeralds.

Emeralds are found all over the world in countries such as Afghanistan, Australia, Austria, Brazil,[23] Bulgaria, Cambodia, Canada, China, Egypt, Ethiopia, France, Germany, India, Italy, Kazakhstan, Madagascar, Mozambique, Namibia, Nigeria, Norway, Pakistan, Russia, Somalia, South Africa, Spain, Switzerland, Tanzania, the United States, Zambia, and Zimbabwe.[1] In the US, emeralds have been found in Connecticut, Montana, Nevada, North Carolina, and South Carolina.[1] In Canada, in 1997 emeralds were discovered in the Yukon.[24]

Origin determinations

Since the onset of concerns regarding diamond origins, research has been conducted to determine if the mining location could be determined for an emerald already in circulation. Traditional research used qualitative guidelines such as an emerald’s color, style and quality of cutting, type of fracture filling, and the anthropological origins of the artifacts bearing the mineral to determine the emerald's mine location. More recent studies using energy dispersive X-ray spectroscopy methods have uncovered trace chemical element differences between emeralds; even emeralds mined within close proximity to one another. American gemologist David Cronin and his colleagues have extensively examined the chemical signatures of emeralds resulting from fluid dynamics and subtle precipitation mechanisms, and their research demonstrated the chemical homogeneity of emeralds from the same mining location and the statistical differences that exist between emeralds from different mining locations, including those between the three locations: Muzo, Coscuez, and Chivor, in Colombia, South America.[25]

Synthetic emerald

Emerald showing its hexagonal structure

Both hydrothermal and flux-growth synthetics have been produced, and a method has been developed for producing an emerald overgrowth on colorless beryl. The first commercially successful emerald synthesis process was that of Carroll Chatham, likely involving a lithium vanadate flux process, as Chatham's emeralds do not have any water and contain traces of vanadate, molybdenum and vanadium.[26] The other large producer of flux emeralds was Pierre Gilson Sr., whose products have been on the market since 1964. Gilson's emeralds are usually grown on natural colorless beryl seeds, which are coated on both sides. Growth occurs at the rate of 1 mm per month, a typical seven-month growth run produces emerald crystals 7 mm thick.[27]

Hydrothermal synthetic emeralds have been attributed to IG Farben, Nacken, Tairus, and others, but the first satisfactory commercial product was that of Johann Lechleitner of Innsbruck, Austria, which appeared on the market in the 1960s. These stones were initially sold under the names 'Emerita' and 'Symeralds', and they were grown as a thin layer of emerald on top of natural colorless beryl stones. Later, from 1965 to 1970, the Linde Division of Union Carbide produced completely synthetic emeralds by hydrothermal synthesis. According to their patents (attributable to E.M. Flanigen),[28] acidic conditions are essential to prevent the chromium (which is used as the colorant) from precipitating. Also, it is important that the silicon-containing nutrient be kept away from the other ingredients to prevent nucleation and confine growth to the seed crystals. Growth occurs by a diffusion-reaction process, assisted by convection. The largest producer of hydrothermal emeralds today is Tairus, which has succeeded in synthesizing emeralds with chemical composition similar to emeralds in alkaline deposits in Colombia, and whose products are thus known as “Colombian created emeralds” or “Tairus created emeralds”.[29] Luminescence in ultraviolet light is considered a supplementary test when making a natural versus synthetic determination, as many, but not all, natural emeralds are inert to ultraviolet light. Many synthetics are also UV inert.[30]

Emerald made by hydrothermal synthesis

Synthetic emeralds are often referred to as 'created', as their chemical and gemological composition is the same as their natural counterparts. The U.S. Federal Trade Commission (FTC) has very strict regulations as to what can and what cannot be called a 'synthetic' stone. The FTC says: '§ 23.23(c) It is unfair or deceptive to use the word 'laboratory-grown', 'laboratory-created', '[manufacturer name]-created', or 'synthetic' with the name of any natural stone to describe any industry product unless such industry product has essentially the same optical, physical, and chemical properties as the stone named.'[11]

In culture and lore

Emerald is regarded as the traditional birthstone for May as well as the traditional gemstone for the astrological signs of Cancer.[31]

One of the quainter anecdotes about emeralds was told by the 16th-century historian Brantôme, who referred to the many impressive emeralds the Spanish under Cortez had brought back to Europe from Latin America. On one of Cortez's most notable emeralds he had the text engraved, Inter Natos Mulierum non sur-rexit mayor ('Among those born of woman there hath not arisen a greater,' Matthew 11:11) which referred to John the Baptist. Brantôme considered engraving such a beautiful and simple product of nature sacrilegious and considered this act the cause for Cortez's loss of an extremely precious pearl (to which he dedicated a work, A beautiful and incomparable pearl), and even for the death of King Charles IX of France, who died soon afterward.[32]

The chief deity of one of India's most famous temples, the Meenakshi Amman Temple in Madurai, is the goddess Meenakshi, whose idol is traditionally thought to be made of emerald.[33]

Notable emeralds

EmeraldOriginSizeLocation
Bahia Emerald[34]Brazil, 2001180,000 carats, crystals in host rockLos Angeles County Sheriff's Department[35]
Carolina Emperor[36][37]United States, 2009310 carats uncut, 64.8 carats cutNorth Carolina Museum of Natural Sciences, Raleigh
Chalk EmeraldColombia38.40 carats cut, then recut to 37.82 caratsNational Museum of Natural History, Washington
Duke of Devonshire EmeraldColombia, before 18311,383.93 carats uncutNatural History Museum, London
Emerald of Saint Louis[38]Austria, probably Habachtal51.60 carats cutNational Museum of Natural History, Paris
Gachalá Emerald[39]Colombia, 1967858 carats uncutNational Museum of Natural History, Washington
Mogul Mughal EmeraldColombia, 1107 A.H. (1695-1696 AD)217.80 carats cutMuseum of Islamic Art, Doha, Qatar
Patricia Emerald[40]Colombia, 1920632 carats uncut, dihexagonal (12 sided)American Museum of Natural History, New York
Mim Emerald[41]Colombia, 20141,390 carats uncut, dihexagonal (12 sided)Mim Museum, Beirut

Gallery

  • Emerald on quartz, from Carnaiba Mine, Pindobaçu, Campo Formoso ultramafic complex, Bahia, Brazil

  • The Chalk Emerald ring, containing a top-quality 37-carat emerald, in the U.S. National Museum of Natural History

  • Emerald crystals

  • A 5-carat emerald from Muzo with hexagonal cross-section

  • Gachalá Emerald, one of the largest gem emeralds in the world, at 858 carats (171.6 g). Found in 1967 at La Vega de San Juan mine in Gachalá, Colombia. Housed at the National Museum of Natural History in Washington, D.C.

  • Rough emerald crystals from Panjshir Valley Afghanistan

  • Large, di-hexagonal prismatic crystal of 1,390 carats uncut with a beautiful deep green color. It is transparent and features few inclusions in the upper 2/3, and is translucent in the lower part. Housed at the Mim Museum, Beirut, Lebanon.

See also

Organic chemistry david klein pdf download 2017

References

  1. ^ abc'Emerald at Mindat'. Mindat.org. July 19, 2010. Archived from the original on July 12, 2010. Retrieved July 30, 2010.
  2. ^ abHurlbut, Cornelius S. Jr. and Kammerling, Robert C. (1991) Gemology, John Wiley & Sons, New York, p. 203, ISBN0-471-52667-3.
  3. ^'Emerald Quality Factors'. GIA.edu. Gemological Institute of America. Archived from the original on November 2, 2016. Retrieved November 1, 2016.
  4. ^Harper, Douglas. 'emerald'. Online Etymology Dictionary.
  5. ^ abcWise, R. W. (2001) Secrets of the Gem Trade: the connoisseur's guide to precious gemstones. Brunswick House Press, p. 108, ISBN0-9728223-8-0.
  6. ^Read, Peter (2008) Gemmology, 3rd rev. ed., NAG Press, p. 218, ISBN0719803616.
  7. ^Grading Fancy-Color DiamondsArchived November 2, 2014, at the Wayback Machine. Gemological Institute of America
  8. ^Bonewitz, R. (2005). Rock and gem. New York: DK Pub. pp. 292-293. ISBN0756633427.
  9. ^Emerald Quality FactorsArchived February 23, 2014, at the Wayback Machine. Gemological Institute of America.
  10. ^Liccini, Mark. Understanding Emerald Enhancements and TreatmentsArchived December 21, 2014, at the Wayback Machine. International Gem Society
  11. ^ ab'Guides for the Jewelry, Precious Metals, and Pewter Industries'. U.S. Federal Trade Commission. May 30, 1996. Archived from the original on September 7, 2008. Retrieved July 30, 2010.
  12. ^Read, P. G. Gemmology. Elsevier. p. 180. ISBN9781483144672. Archived from the original on March 31, 2017. Retrieved March 30, 2017.
  13. ^Matlins, Antoinette Leonard; Bonanno, Antonio C. Jewelry & Gems, the Buying Guide: How to Buy Diamonds, Pearls, Colored Gemstones, Gold & Jewelry with Confidence and Knowledge. Gemstone Press. p. 126. ISBN9780943763712. Archived from the original on March 30, 2017. Retrieved March 30, 2017.
  14. ^Giuliani G, Chaussidon M, Schubnel HJ, Piat DH, Rollion-Bard C, France-Lanord C, Giard D, de Narvaez D, Rondeau B (2000). 'Oxygen Isotopes and Emerald Trade Routes Since Antiquity'(PDF). Science. 287 (5453): 631–3. Bibcode:2000Sci...287..631G. doi:10.1126/science.287.5453.631. PMID10649992. Archived(PDF) from the original on August 7, 2011.
  15. ^'Romans organized the mines as a multinational business...' Finlay, Victoria. Jewels: A Secret History (Kindle Location 3098). Random House Publishing Group. Kindle Edition.
  16. ^Badawy, Manuela (June 13, 2012). 'Emeralds seek the 'De Beers' treatment'. Reuters. Archived from the original on December 19, 2012. Retrieved June 14, 2012.
  17. ^Dydyński, Krzysztof (2003). Colombia. Lonely Planet. p. 21. ISBN0-86442-674-7.
  18. ^Branquet, Y. Laumenier, B. Cheilletz, A. & Giuliani, G. (1999). 'Emeralds in the Eastern Cordillera of Colombia. Two tectonic settings for one mineralization'. Geology. 27 (7): 597–600. Bibcode:1999Geo....27..597B. doi:10.1130/0091-7613(1999)027<0597:EITECO>2.3.CO;2.CS1 maint: Multiple names: authors list (link)
  19. ^Carrillo, V. (2001). Compilación y análisis de la información geológica referente a la explotación esmeraldífera en Colombia. Informe de contrato 124. INGEOMINAS
  20. ^Wacaster, Susan (March 2012). '2010 Minerals Yearbook: Colombia [ADVANCE RELEASE]'(PDF). United States Geological Survey. Archived(PDF) from the original on August 13, 2012. Retrieved August 7, 2012.
  21. ^Emerald Mining Areas in ColombiaArchived September 29, 2010, at the Wayback Machine, with location map of these three districts.
  22. ^Behling, Steve and Wilson, Wendell E. (January 1, 2010) 'The Kagem emerald mine: Kafubu Area, Zambia', The Mineralogical Record – via HighBeam (subscription required)Archived May 10, 2013, at the Wayback Machine
  23. ^'Maior esmeralda do mundo, encontrada no Brasil, será leiloada no CanadáArchived April 7, 2014, at the Wayback Machine'. UOL (2012-01-18)
  24. ^Emeralds in the Yukon TerritoryArchived March 31, 2014, at the Wayback Machine. Yukon Geological Survey.
  25. ^Cronin, David; Rendle, Andy (2012). 'Determining the geographical origins of natural emeralds through nondestructive chemical fingerprinting'. Journal of Gemmology. 33: 1–13. Archived from the original on November 17, 2015.
  26. ^O'Donoghue, Michael (1988). Gemstones. Dordrecht: Springer Netherlands. p. 310. ISBN9789400911918. Archived from the original on March 30, 2017.
  27. ^Nassau, K. (1980) Gems Made By Man, Gemological Institute of America, ISBN0-87311-016-1.
  28. ^Geological Magazine 'Hydrothermal process for growing crystals having the structure of beryl in an alkaline halide medium' U.S. Patent 3,567,642 Issue date: March 2, 1971
  29. ^Schmetzer, Karl; Schwartz, Dietmar; Bernhardt, Heinz-Jurgen; Tobias Hager (2006–2007). 'A new type of Tairus hydrothermally-grown synthetic emerald, colored by vanadium and copper'(PDF). Journal of Gemmology of Gemmological Association of Great Britain. 30 (1–2): 59–74. Archived from the original(PDF) on July 11, 2011.
  30. ^Hurlbut, Cornelius S. Jr. and Kammerling, Robert C. (1991) Gemology, John Wiley & Sons, New York, p. 81, ISBN0-471-52667-3.
  31. ^Morgan, Diane (2007). From Satan's crown to the holy grail : emeralds in myth, magic, and history. Westport, Conn. [u.a.]: Praeger. p. 171. ISBN9780275991234. Archived from the original on March 30, 2017. Retrieved March 30, 2017.
  32. ^Kunz, George Frederick (1915). Magic of Jewels and Charms. Philadelphia: Lippincott Company. p. 305. ISBN0-7661-4322-8. Archived from the original on October 17, 2012.
  33. ^'Meenakshi Temple - Meenakshi Temple of Madurai, Meenakshi Amman Temple Madurai India'. www.madurai.org.uk. Archived from the original on March 17, 2016. Retrieved January 18, 2016.
  34. ^Allen, Nick (September 24, 2010). 'Judge to decide who owns 250 million Bahia emerald.html'. The Daily Telegraph, UK. Archived from the original on September 28, 2010. Retrieved December 31, 2010.
  35. ^'The Curse of the Bahia Emerald, a Giant Green Rock That Ruins Lives'. wired.com.
  36. ^Gast, Phil (September 1, 2010). 'North Carolina emerald: Big, green and very rare'. CNN. Cable News Network (Turner Broadcasting System, Inc.). Archived from the original on September 25, 2013. Retrieved October 8, 2013.
  37. ^Stancill, Jane (March 16, 2012). 'N.C. gems to shine at museum'. The News & Observer. The News & Observer Publishing Co. Archived from the original on March 27, 2012. Retrieved October 8, 2013.
  38. ^'Emeraude de Saint Louis - St Louis Emerald'. CRPG: Le Centre de Recherches Pétrographiques et Géochimiques. Archived from the original on March 4, 2016. Retrieved February 8, 2017.
  39. ^'Gachala Emerald'. National Museum of Natural History. Smithsonian Institution. 2017. Archived from the original on February 11, 2017. Retrieved February 8, 2017.
  40. ^'Patricia Emerald'. AMNH. Archived from the original on September 5, 2015. Retrieved August 22, 2015.
  41. ^Bouillard, J.-C. and Jeanne-Michaud, A. (2016) '101 minéraux et pierres précieuses - qu'il faut avoir vus dans sa vie'. Hors collection, Dunod. ISBN2100742272.

Further reading

  • Ali, Saleem H. (2006). The Emerald City: Emerald mining in Brazil (+Gemstone mining in other countries) http://www.uvm.edu/envnr/gemecology/brazil.html
  • Cooper, J. C. (ed.) (1992). Brewer's Myth and Legend. New York: Cassell Publishers Ltd. ISBN0-304-34084-7.
  • Hurlbut, Cornelius S.; Klein, Cornelis (1985). Manual of Mineralogy (20th ed.). New York: John Wiley and Sons. ISBN0-471-80580-7.
  • Sinkankas, John (1994). Emerald & Other Beryls. Prescott, Ariz.: Geoscience Press. ISBN0-8019-7114-4.
  • Tavernier, Jean-Baptiste (1925 [1676]). Travels in India (second edition), Volume II. Edited by William Crooke and translated by V. Ball. London: Oxford University Press.
  • Weinstein, Michael (1958). The World of Jewel Stones. New York: Sheriden House. OCLC519758.
  • Wise, Richard W. (2003). Secrets of the Gem Trade: The Connoisseur's Guide to Precious Gemstones. Lenox, Mass.: Brunswick House Press. ISBN9780972822398. OCLC55662640. Online Emerald chapters.

External links

Wikimedia Commons has media related to Emeralds.

Organic Chemistry David Klein Pdf Download Free

  • ICA's Emerald Page International Colored Gemstone Association Emerald Page
Retrieved from 'https://en.wikipedia.org/w/index.php?title=Emerald&oldid=898219065'

ForMemRS[1]
BornOctober 21, 1877
Halifax, Nova Scotia, Canada[2]
DiedFebruary 20, 1955 (aged 77)
NationalityCanadian-American
Known for
  • DNA transmits heredity
Awards
  • Copley Medal (1945)
  • Albert Lasker Award for Basic Medical Research (1947)
Scientific career
FieldsMolecular biology[3]
InstitutionsRockefeller University Hospital

Oswald Theodore Avery Jr. (October 21, 1877 – February 20, 1955) was a Canadian-American physician and medical researcher. The major part of his career was spent at the Rockefeller University Hospital in New York City. Avery was one of the first molecular biologists and a pioneer in immunochemistry, but he is best known for the experiment (published in 1944 with his co-workers Colin MacLeod and Maclyn McCarty) that isolated DNA as the material of which genes and chromosomes are made.[4][5][6]

The Nobel laureateArne Tiselius said that Avery was the most deserving scientist not to receive the Nobel Prize for his work,[7] though he was nominated for the award throughout the 1930s, 1940s, and 1950s.[8][9]

The lunar craterAvery was named in his honor.

Family and early life[edit]

Avery was born in Halifax, Nova Scotia in 1877 to Francis Joseph Avery, a Baptist minister, and his wife Elizabeth Crowdy. The couple had immigrated from Britain in 1873. Oswald Avery was born and grew up in a small wooden row house on Moran Street in the North End of Halifax, now a designated heritage building.[10] When Avery was 10, his family moved to the Lower East Side of New York City. As a youth, Avery studied music at first and then switched to medicine at college, earning his medical degree and beginning a practice in 1904.[11]

Breakthrough discovery[edit]

For many years, genetic information was thought to be contained in cellprotein. Continuing the research done by Frederick Griffith in 1927, Avery worked with MacLeod and McCarty on the mystery of inheritance. He had received emeritus status from the Rockefeller Institute in 1943, but continued working for five years, though by that time he was in his late sixties. Techniques were available to remove various organic compounds from bacteria, and if the remaining organic compounds were still able to cause R strain bacteria to transform then the substances removed could not be the carrier of genes. S-strain bacteria first had the large cellular structures removed. Then they were treated with proteaseenzymes, which removed the proteins from the cells before the remainder was placed with R strain bacteria. The R strain bacteria transformed, meaning that proteins did not carry the genes causing the disease. Then the remnants of the R strain bacteria were treated with a deoxyribonuclease enzyme which removed the DNA. After this treatment, the R strain bacteria no longer transformed. This indicated that DNA was the carrier of genes in cells.[12]

Alfred Hershey and Martha Chase furthered Avery's research in 1952 with the Hershey–Chase experiment. These experiments paved the way for Watson and Crick's discovery of the helical structure of DNA, and thus the birth of modern genetics and molecular biology. Of this event, Avery wrote in a letter to his youngest brother Roy, a bacteriologist at the Vanderbilt School of Medicine: 'It's lots of fun to blow bubbles but it's wiser to prick them yourself before someone else tries to.'[13]

Nobel laureate Joshua Lederberg stated that Avery and his laboratory provided 'the historical platform of modern DNA research' and 'betokened the molecular revolution in genetics and biomedical science generally'.

Bibliography[edit]

The collected papers of Avery are stored at the Tennessee State Library and Archives and at the Rockefeller Archive. Many of his papers, poems, and hand written lab-notes are available at the National Library of Medicine in the Oswald T. Avery Collection, the first of their Profiles in Science series.[14]

Organic Chemistry David Klein Pdf Download

References[edit]

  1. ^Dubos, R. J. (1946). 'Oswald Theodore Avery 1877–1955'. Biographical Memoirs of Fellows of the Royal Society. 2: 35–48. doi:10.1098/rsbm.1956.0003. JSTOR769474.
  2. ^ ab'The Oswald T. Avery Collection. Biographical Information'. Profiles in Science. US National Library of Medicine (NIH). Retrieved 18 May 2018.
  3. ^Barciszewski, J. (1995). 'Pioneers in molecular biology: Emil Fischer, Erwin Schrodinger and Oswald T. Avery'. Postepy biochemii. 41 (1): 4–6. PMID7777433.
  4. ^Hotchkiss, R. D. (1965). 'Oswald T. Avery: 1877–1955'. Genetics. 51: 1–10. PMID14258070.
  5. ^'Oswald Theodore Avery, 1877–1955'. Journal of General Microbiology. 17 (3): 539–549. 1957. doi:10.1099/00221287-17-3-539. PMID13491790.
  6. ^Dochez, A. R. (1955). 'Oswald Theodore Avery, 1877–1955'. Transactions of the Association of American Physicians. 68: 7–8. PMID13299298.
  7. ^Judson, Horace (2003-10-20). 'No Nobel Prize for Whining'. The New York Times. Retrieved 2007-08-03.
  8. ^Erica Westly (October 6, 2008). 'No Nobel for You: Top 10 Nobel Snubs'. Scientific American.
  9. ^Reichard, P. (2002). 'Osvald T. Avery and the Nobel Prize in Medicine'(PDF). Journal of Biological Chemistry. 277 (16): 13355–13362. doi:10.1074/jbc.R200002200. PMID11872756.
  10. ^'Avery House', Canada's Historic Places
  11. ^Rene Dubos, 'Fess Avery: The Man and the Scientist', Institute to University: A Seventy-Fifth Anniversary Colloquium June 8, 1973, The Rockefeller University (1977) p. 46-49.
  12. ^Avery, Oswald T.; MacLeod, Colin M.; McCarty, Maclyn (February 1, 1944). 'Studies on the Chemical Nature of the Substance Inducing Transformation of Pneumococcal Types - Induction of Transformation by a Desoxyribonucleic Acid Fraction Isolated from Pneumococcus Type III'. Journal of Experimental Medicine. 79 (2): 137–158. doi:10.1084/jem.79.2.137. PMC2135445. PMID19871359.
  13. ^Davies, Kevin (2001). Cracking the Genome: Inside the Race to Unlock Human DNA. The Free Press.
  14. ^'The Oswald T. Avery Collection'. National Library of Medicine. Retrieved April 28, 2011.

Organic Chemistry David Klein Pdf Download Full

Further reading[edit]

Organic Chemistry David Klein 3rd Edition Pdf Download

  • Diamond, Arthur M. (1982). 'Avery's 'Neurotic Reluctance''. Perspectives in Biology and Medicine. 26 (1): 132–136. CiteSeerX10.1.1.587.6127. doi:10.1353/pbm.1982.0002.
  • René Dubos, The Professor, the Institute, and DNA: Oswald T. Avery, His Life and Scientific Achievements, 1976, Paul & Company, ISBN0-87470-022-1
  • Lehrer, Steven (2006). Explorers of the Body (2nd ed.). United States: iUniverse, Inc. ISBN0-595-40731-5.
  • Sri Kantha, S (1989). 'Avery's non-recognition in Nobel awards'. BioEssays. 10: 131. doi:10.1002/bies.950100411.
  • Avery, O T; Macleod C M; McCarty M (October 2000). 'Studies on the chemical nature of the substance inducing transformation of pneumococcal types: Induction of transformation by a desoxyribonucleic acid fraction isolated from Pneumococcus type III. Oswald Theodore Avery (1877–1955)'. Clin. Orthop. Relat. Res.379 (379 Suppl): S3–8. doi:10.1097/00003086-200010001-00002. PMID11039746.
  • Austrian, R (July 1999). 'Oswald T. Avery: the Wizard of York Avenue'. Am. J. Med.107 (1A): 7S–11S. doi:10.1016/S0002-9343(99)00109-6. PMID10451004.
  • Lederberg, J (February 1994). 'The transformation of genetics by DNA: an anniversary celebration of Avery, MacLeod and McCarty (1944)'. Genetics. 136 (2): 423–6. PMC1205797. PMID8150273.
  • Amsterdamska, O (1993). 'From pneumonia to DNA: the research career of Oswald T. Avery'. Historical Studies in the Physical and Biological Sciences : HSPS / Office of History of Science and Technology, University of California, Berkeley. 24 (pt 1): 1–40. PMID11623400.
  • Russell, N (December 1988). 'Oswald Avery and the origin of molecular biology'. The British Journal for the History of Science. 21 (71 Pt 4): 193–400. doi:10.1017/S0007087400025310. PMID11621687.
  • Pirie, N W (December 1972). 'Avery in retrospect'. Nature. 240 (5383): 572. doi:10.1038/240572a0. PMID4568407.
  • Coburn, A F (1969). 'Oswald Theodore Avery and DNA'. Perspect. Biol. Med. 12 (4): 623–30. PMID4900165.
  • Kay, Alan (1970). 'Avery, Oswald T.'. Dictionary of Scientific Biography. 1. New York: Charles Scribner's Sons. pp. 342–343. ISBN0-684-10114-9.
  • Key Participants: Oswald T. Avery - Linus Pauling and the Race for DNA: A Documentary History
  • Oswald T. Avery Collection (1912-2005) - National Library of Medicine finding aid
  • The Oswald T. Avery Collection - Profiles in Science, National Library of Medicine

Organic Chemistry David Klein 3rd Edition Pdf Free Download

Retrieved from 'https://en.wikipedia.org/w/index.php?title=Oswald_Avery&oldid=889936355'

Coments are closed